5 September 2023 (Tuesday-Room A)
| 09:00-10:00 | Registration |
| 10:00-11.00 | Opening Ceremony |
| 11:00-11.30 | Coffee/Tea Break |
| Oxidative stress | |
| 11:30-13.00 | Session Chairmen: Ramazan Bal, Dimitra Gkika
K1- Keynote Speaker: Valerian Kagan (Pittsburgh, USA) Decoding oxidative stress in cell death by redox lipidomics S1- Speaker; Hülya Bayır (New York, USA) Mitochondrial metabolism in sepsis induced organ dysfunction |
| 13:30-15:00 | Lunch |
| TRP channels and cancer | |
| 15:00-16:15 | Session Chairmen: Ömer Çelik, Şefik Dursun
S2- Speaker; Dimitra Gkika (Lille, France) Non genomic regulation of TRPM8: from thermosensation to cancer OP-1) Dana Cucu (Bucharest, Romania) Modulation of the TRPA1 function and traffic by reactive oxygen species OP-2) Mümin Alper Erdoğan (İzmir, Turkiye) Anti-cancer effects of siRNA-mediated targeting of NaV1.7 channel in pancreatic cancer cell lines OP-3) Sevtap Kılınç (Ankara, Türkiye) The effect of topiramate on oxidative and nitrosative stress, inflammation and apoptosis in non-alcoholic fatty liver disease |
| 16:15-17:00 | Coffee/Tea Break |
| Nutrition and oxidative stress | |
| 17:00-17:45 | Session Chairmen: Süleyman Kutluhan, Tarik Smani
S3- Speaker; Cem Ekmekcioğlu (Wien, Austria) Nutrition and COVID-19 OP-4) Asal Ghaffari Zaki (Istanbul, Türkiye) pH-Control: a novel approach for manipulation of intracellular pH |
| 18:30-19.30 | Dinner in the Restaurant of SDU University Hospital |
6 September 2023 (Wednesday-Room A)
Neuroscience and TRP channels-1
| 09:00-10:00 | Session Chairmen: Emrah Eroğlu, Alexander G. Dimitrov
K2- Keynote Speaker: Peter A. McNaughton (London, UK) How do immune cells navigate to their targets? What clinical benefit can we achieve by inhibiting neutrophil invasion S4– Speaker; Zhigang Xiong (Atlanta, USA) TRPM7 as a novel target for neurological disorders |
| 10:00-10:30 | Coffee/Tea Break |
| Neuroscience and TRP channels-2 | |
| 10:30-12:00 | Session Chairmen: Mümin Alper Erdoğan, Leyla Şahin
S5- Speaker: Yassine El Hiani (Halifax, Canada) TRPML1 controls mitochondrial function and cellular metabolism of TNBC cells S6– Speaker; Mustafa Nazıroğlu (Isparta, Türkiye) The interaction between hypoxia-induced NMDA receptor activation and TRPM2 channel OP-5) Alexander G. Dimitrov (Sofia, Bulgaria) Ca as a center of cellular energetics involved in maintaining the resting state of excitable cells OP-6) Kaan Erbakan (Ordu, Türkiye) Addictive behavior towards opioids and the role of vanilloid TRPV1 channels in its molecular mechanisms |
| 12:30-14:00 | Lunch |
| TRP channels and diseases | |
| 14.00-15.00 | Session Chairmen: Ahmi Öz, Kemal Ertilav
S7– Speaker; Tarik Smani (Seville, Spain) TRPC and Orai channels in ischemic heart disease OP-7) Alexander Sobolevsky (New York, USA) Structural mechanisms of TRPM7 activation and inhibition OP-8) Emel Sokullu (Istanbul, Türkiye) Effects of differentiation on SH-SY5Y human neuroblastoma cell line for TRPM channel activation |
| 15.00-15.30 | Coffee/Tea Break |
| 15.30-17.00 | Session Chairmen: Yener Yazğan, Emel Sokullu
S8– Speaker; Ramazan Bal (Gaziantep, Türkiye) Oxidative stress induced ion channels couple metabolic status to resting membrane potential of the neurons in the mouse ventral cochlear nucleus S9– Speaker; Salina Muhamad (Selangor, Malaysia) Metal oxide nanoparticles in cosmetic: possibility of inducing oxidative stress OP-9) Laszlo Pecze (Freiburg, Switzerland) Altered metabolism and calcium signaling in Down syndrome |
| 09.00-17.30 | Poster Presentations P1 – P50
Poster Discussion time: 17.00-17.30 |
| 18.00-19.00 | Visit Hand Made Carpet Museum in Isparta |
| 19.00-21.00 | Dinner in Isparta Kirazlıdere Social Facilities |
6 September 2023 (Wednesday-Room B)
| 09:00- 10:00 | Session Chairmen: Laszlo Pecze, Mehmet Çay
TOP-1) Adem AHLATÇI (Van, Turkiye) Neuroprotective effect of chrysin in PTZ-induced neurotoxicity in SH-SY5Ycells: Role of TRPM2 channel TOP-2) Selahattin AYDEMİR (Van, Turkiye) Meta-analysis of the effect of Fasciola hepatica infections on the total antioxidant capacity of the host TOP-3) Gözde ARKALI (Elazığ, Turkiye) The effect of endoplasmic reticulum stress induced apoptosis and autophagy in myocardial hypertrophy caused by hyperthyroidism: PERK/ATF4/CHOP signaling pathway TOP-4) Edanur GÜLER EKMEN (Elazığ, Türkiye) The effect of zingerone on Sirt1/Nrf2/HO-1 signaling pathway and spermatological parameters in diabetic rats |
| 10.00-10.30 | Coffee/Tea Break |
| 10.30-12:15 | Session Chairmen: Kenan Yıldızhan, Salina Muhamad
TOP-5) Murat Saygın (Van, Turkiye) Oxidative Stress in Neurocysticercosis TOP-6) Zeki Serdar ATAİZİ (Eskişehir, Türkiye) The interaction between spinal cord injury and TRPV1 channel TOP-7) Kemal ERTİLAV (Isparta, Türkiye) The antioxidant administration modulates traumatic brain injury through the modulation of TRPV1 channel Session Chairmen: Cem Ekmekcioğlu, Zeki Serdar Ataizi TOP-8) Zeynep Sarımermer Yücel (Kayseri, Türkiye) The effect of lavandula stoechas essential oil on nerve regeneration in rats with sciatic nerve injury TOP-9) Seval Musuroglu Keloglan (Adıyaman, Türkiye) The effect of melatonin and treadmill exercise on social isolation stress related to hippocampal BDNF, GFAP and SNAP25 gene expression levels in adult rats TOP-10) Gülten Ateş Uluçay (İstanbul, Türkiye) Anti-oxidant effects of melatonin on sepsis-induced oxidative stress in liver tissue of rats TOP-11) Merve Tunçyürekli (Van, Türkiye) The implications of combined metformin and atorvastatin treatment on oxidative stress/ antioxidant status in the gastrocnemius muscle of treadmill exercised STZ-diabetic rats |
| 18.00-19.00 | Visit Hand Made Carpet Museum in Isparta |
| 19:00-21.00 | Dinner in Isparta Kirazlıdere Social Facilities |
7 September 2023 (Thursday-Room A)
| Ferroptosis and oxidative stress | |
| 09.00–10.00 | Session Chairmen: Valerian Kagan, Dana Cucu
S10– Speaker; Ofer Beharier (Jerusalem, Israel) Anti-ferroptotic drugs as a novel tool to reduce placental sFlt-1 secretion: a potential treatment for preeclampsia S11- Speaker; Karolina Mikulska-Ruminska (Torun, Poland) The role of computational modeling in uncovering mechanisms of oxidative stress in regulated cell death |
| 10.00-10.30 | Coffee/Tea Break with Family Photo |
| 10.30-11.30 | Session Chairmen: Hülya Bayır, Peter A. McNaughton, Alexander Sobolevsky
Room A Young Speaker-1: İpek Dağ (Isparta, Turkiye) The Involvement of Mitochondrial Reactive Oxygen Species-Mediated Transient Receptor Potential Canonical 3 Activation in Itch Young Speaker-2: Büşra Oğuz (Isparta, Turkiye) The activation of TRPM8 induces hyperosmotic stimuli-induced nociception in dental Afferents Young Speaker-3: Ayshan Aliyeva (Isparta, Turkiye) Orthodontic teeth movement-induced pain and TRPV1 channel Young Speaker-4: Tarkan Eşenli (Isparta, Turkiye) The interaction between melatonin and TRPM2 channel in traumatic brain injury Young Speaker-5: Maysa Allaberdyyeva (Isparta, Turkiye) Epilepsy and TRPV1 channels Young Speaker-6: İlayda Reyhan Kundakçı (Konya, Turkiye) The interaction between oxidative stress-induced TRP channel activation and Alzheimer’s disease Young Speaker-7: Nefise Tilkici (Sivas, Turkiye) Selenium modulates experimental dementia via inhibition of TRPM2 and TRPV1 channels Young Speaker-8: Semih Yasin Çelenk (Sivas, Turkiye) Dexmedetomidine, cerebral ischemia and TRPV1 channel |
| 11.30-12.00 | Fruit (Fresh Grape) or Ice cream |
| 12.00–13.45 | Session Chairmen: Yassine El Hiani, Zhigang Xiong, Emrah Eroğlu
Room B |
| Young Speaker-9: Ahmet Turan İnce (Sivas, Turkiye)
Are there actions of TRPM2 and TRPV1 in the etiology of fibromyalgia? Protective role of selenium Young Speaker-10: Doğa Karaköylü (Isparta, Turkiye) The interaction between eicosapentaenoic acid-induced TRPM2 activation and cisplatin in the glioblastoma cell death Young Speaker-11: Asiye Kiliç (Ankara, Turkiye) Anticancer action of bee venom melittin and TRPM2 channels Young Speaker-12: Emre Can Çavuş (Isparta, Turkiye) NMDA stimulation induces TRPM2 activation in hypoxia Young Speaker-13: Gülçin Kibar (Isparta, Turkiye) Melatonin attenuates hypoxia-induced oxidative neurotoxicity via inhibition of TRPV4 in a neuronal cell line Young Speaker-14: Alperen Yurdakul (Ankara, Turkiye) Curcumin and selenium modulate diabetic neuropathic pain via the inhibition of TRPM7 channel Young Speaker-15: Buğra Sarısözen Çelenk (Tekirdağ, Turkiye) Silver nanoparticles kills glioblastoma cells via the activation of TRPM2 |
| 13.45–14.30 | Lunch |
| 14:30-19.30 | FREE TIME and SOCIAL ACTIVITIES |
| 19.30–21:30 | Dinner in Eğirdir |
8 September 2023 (Friday)
| Ca2+ and redox system | |
| 09:00–10:00 | Session Chairmen: Yassine El Hiani, Mohd Aswadi
S12– Speaker; Emrah Eroğlu (Istanbul, Türkiye) Genetic biosensors and chemogenetic tools: Unlocking redox biology through multiparametric imaging OP-10) Seyit Kale (Izmir, Türkiye) Molecular simulation approaches in elucidating the biophysics of divalent cation sensing OP-11) Hande Yüceer Korkmaz (İstanbul, Türkiye) Investigation of TNF alpha, IL6, Paraoxonase, and Superoxide Dismutase enzyme activities in obsessive compulsive disorder |
| 10.00-10.30 | Coffee/Tea Break |
| Neurodegenerative diseases, Oxidative stress and Methods | |
| 10.30–11:45 | Session Chairmen: Seyit Kale, Ömer Çelik
S13– Speaker; Alain Buisson (Grenoble, France) Neuronal and astrocytic calcium signalling disturbances in Alzheimer’s disease: toward the validation of TRPA1 as a therapeutic target K3 – Keynote Speaker: Özcan EREL (Ankara, Türkiye) A colorimetric method to measure oxidized reduced and total glutathione levels in tissue |
| 11.45-12.45 | AWARD AND CLOSING CEREMONY |
| 12.45-14.00 | Lunch |
| 14.00-19.00 | FREE TIME AND BARBEQUE PARTY (TURKISH KEBAP) | |
| Poster Award, Young Investigator Award and Closing Ceremony
Young Investigator Award Committee Room A 1- Hülya Bayır 2- Peter A. McNaughton 3- Alexander Sobolevsky Room B 1-Yassine El Hiani 2- Zhigang Xiong 3- Emrah Eroğlu National (Abstracts from Türkiye) Award Committee 1- Süleyman Kaplan (Chair) 2- Şefik Dursun 3- Salina Muhamad 4- Mehmet Cemal Kahya 5– Betül Yazğan
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